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Preliminary Program NK 2009 – FREIBURG
Wednesday Nov 4, 2009
12.00 - 18.00Registration
12.00 – 14.00Coffee
14.00 – 14.15Welcome address
14.15 – 15.00KEYNOTE LECTURE: Thomas Boehm, TBA
15.00 – 16.15Session 1: NK cells in the clinic I
Chair:
15.00Robert Negrin
NK Cells in Allogeneic Transplantation: a Novel Mechanism of Control of Graft-versus-Host-Disease
15.30Christine Falk
Consequences of CD6-depletion for the composition of NK subsets in haploidentical bone marrow and stem cell transplantation
15.45Paul Fisch
Expansion of alloreactive NK cells in HLA-matched KIR/HLA-ligand mismatched patients following hematopoietic cell transplantation
16.00Jan Spanholtz
Clinical scale generation of functional human NK cells for immunotherapy
16.15 – 16.45Coffee break
16.45 – 18.00Session 2: NK cells in the clinic II
Chair:
16.45Jeroen van Bergen
Evidence for NK cell-mediated rejection of HLA compatible kidney transplants
17.00Katja Kotsch
Targeting NKp46 delays acute graft rejection in a murine model of heterotopic heart transplantation
17.15Tina Baessler
The TNF family member 4-1BB ligand mediates opposite effects in human and mouse NK cells and enables immune evasion of human leukemia cells
17.30Loredana Ruggeri
NK cell alloreactivity in MHC haplotype mismatched transplantation
18.00 – 18.45Poster presentations
x 1 minute presentations
18.45 – 19.45Poster session I
20.00 – 23.00Dinner, Peterhofkeller
Thursday Nov 5, 2009
8.30 – 11.00Session 3: NK cell receptors
Chair:
8.30Werner Held
TBA
9.00Alexander Steinle
NKC-encoded NK receptors and their ligands
9.30Lise Kveberg
Phylogenetic and functional conservation of the NKR-P1G NK receptor in rat and mouse
9.45Hanspeter Pircher
An update on KLRG1
10.00Tina van den Broeck
Unique regulation of Ly49E NK receptor expression
10.15 Lutz Walter
A novel system of polymorphic and diverse NK cell receptors in primates
10.30 – 11.00Coffee break
11.00 – 12.45Session 4: NK cell development, NK cell subsets
Chair:
11.00James Di Santo
Functional Diversity of NKp46+ cell Subsets
11.30Hergen Spits
The relationship of human lymphoid tissue inducer cells and NK cells
12.00Andreas Diefenbach
TBA
12.30Claudia Luther
IL-7Ra+ NK cells develop from novel Lin-CD49b+IL-7Ra+ progenitors
12.45 – 14.00Lunch
14.00 – 15.30Session 5: NK cell education and activation
Chair:
14.00Klas Kärre
TBA
14.30Christian Münz
Human NK cell compartments and their activation by dendritic cells
15.00Yenan Bryceson
Minimal requirements for induction of effector functions by human NK cells upon target cell recognition
15.15Carsten Watzl
Signals regulating the activity of LFA-1 in resting human NK cells
15.30 – 16.00Coffee break
16.00 – 17.30Session 6: NK cell responses/activation
Chair:
16.00Hansgustaf Ljunggren
Activation of human NK cells
16.30Bojan Polic
Dual role of NKG2D in NK cell physiology
17.00Alfonso Martin-Fontecha
Revisiting the role of T-bet in NK cell responses
17.30Margret Ehlers
Role of regulatory (immunosuppressive) NK cells in autoimmunity
17.45 – 18.30Poster presentations
1 minute presentations
18.30 – 19.45Poster session II
20.00Dinner, Castillo
Friday Nov 6, 2009
08.30 – 10.00Session 7: NK cells and cancer
Chair:
08.30Eric Vivier
About the competence of NK cells against cancer
09.00Adelheid Cerwenka
Molecular and functional signatures of tumor infiltrating NK cells
09.15Hugh Reyburn
The common MICA allele MICA*008 is released from cells in exosomes and triggers a marked reduction in NK cell cytotoxic function
09.30Ennio Carbone
NK cell response against the melanoma lymph node colonization
09.45Heike Himmelreich
Role of microRNAs in post-transcriptional regulation of NKG2D ligand expression in human tumor cell lines
10.00 – 10.30Coffee break
10.30 – 11.15Session 8: NK cells and reproduction
Chair:
10.30Francesco Colucci
NK cells in reproduction and cancer
11.00Ashley Moffett
The influence of maternal KIR and fetal and maternal HLA-C genotypes on human reproductive success
11.15 – 11.30Coffee break
11.30 – 13.00Session 9: NK cells and infection
Chair:
11.30Veronique Braud
Primed antigen-specific CD4+ T cells are required for natural killer cell activation in vivo
12.00Simone Häberlein
Differential contribution of IL-12, IL-15 and IL-18 to the activation of NK cells in visceral leishmaniasis
12.15Inpyo Choi
Pseudomonas aeruginosa eliminates NK cells via phagocytosis-induced apoptosis
12.30Andreas Busche
Profound alterations of innate lymphocyte homeostasis in latent murine cytomegalovirus infection
12.45 – 13.00 Closing remarks / Poster prizes
13.00 – 14.00Lunch
14.00Departure